Glycolic acid is one of the alpha-hydroxyacids (AHAs), a group of naturally occurring substances often referred to as "fruit acids" because they are found naturally in various fruits and other foods. In its natural state, glycolic acid is found in sugar cane juice. Leading dermatologists and plastic surgeons worldwide have long appreciated the positive results of AHA treatments. Numerous clinical publications have demonstrated their benefits in improving skin appearance and texture. Improvements have been observed in patients with dry skin, oily and acne-prone skin, and with pigmentation concerns including age spots and melasma.

Many skin problems are caused by or associated with an excessive build-up of dead skin cells that makes the skin thick and dull, and may cause clogged pores. AHAs help to loosen and remove the surface layers of skin, as well as promote more even pigmentation and deeper skin firming effects.