eNewsletter Dermatology Sign Up
Look good, feel great with Beautiful Skin
Crutchfield Dermatology Home Patient Reviews Patient Portal Make a Payment Leading Doctors Best Doctors in America Consumer’s Research Council of America Top Dermatologist for Women Mpls St. Paul Top Doctors Crutchfield Dermatology Awarded 2008 Best of St. Paul for their Excellence in Skin Care Mpls St. Paul Top Doctors Physcian Health Care Heros America's Top Doctors Request Appointment eNewsletter Sign Up
Medical Education Sectiongif

Charles E. Crutchfield III M.D.

47 year old woman notices small dark spots on her lips and inner cheeks developing over 4-6 months. On examination, there are multiple slate blue grey/brown macules on the tongue, lips and inner cheeks. No fingernail involvement. She recently had a complete medical exam with no hormonal abnormalities detected and no history of skin cancer and no history of congenital diseases. No history of GI symptoms or Peutz-Jeghers Syndrome. Otherwise healthy.

What is your diagnosis?

Tongue spots

Diagnosis: Laugier-Hunziker Syndrome

Manifestations and Major Findings: Benign, acquired, lentiginous macular pigmentation of labial and buccal mucosa and nails. Usually develops over 3-9 months.

The condition is not associated with systemic abnormalities (e.g. gastrointestinal polyps) as seen in Peutz Jeghers syndrome. Peutz-Jeghers also presents in infancy and childhood and 2/3 of those affected with Peutz Jeghers also have lesions on the hands and feet.

In this case, interestingly, she was without nail involvement. I reassured her that the condition was benign.

spots in mouth


Tongue spots


An Illustrated Dictionary of Dermatologic Syndromes
Susan Bayliss Mallory MD

Koch SE, LeBoit PE, Odom RB: Laugier-Hunziker syndrome. J Am Acad Dermatol 1987; 16:431-434.

Sterling GB, Libow LF, Grossman ME: Pigmented nail streaks may indicate Laugier-Hunziker syndrome. Cutis 1988; 42:325-326





For more Cases of the month see:
Case of the Month

Cases of the Month Archives

gif gif

Crutchfield Dermatology

651-209-3600       Look Good, Feel Great with Beautiful Skin ™

Prestigious Organizations
MetroDoctors ASDS-Net.org ASCDAS.org NMANET.org aestheticmd.com Better Business Bureua
expert injectorMayo Clinic American Board Dermatology American Medical Med.UMN.edu cosmeticsurgery.org ASNA Top Dermatologist

AAD Fellow Alpha Omega Alpha
Crutchfield Dermatology All Photographs are copyright protected. Unauthorized use is prohibited 651-209-3600

Crutchfield Dermatology
1185 Town Centre Drive Suite 101 Eagan, MN 55123
Call for appointment: 651-209-3600 Fax: 651-209-3601

top 100 places to work

Proudly serving: The greater Twin Cities area, Minneapolis, St. Paul, Edina, Eden Prairie, Eagan, Richfield, Bloomington, Hopkins, Savage, Mendota Heights, St. Louis Park, Wayzata, Plymouth, Maple Grove, Crystal, Roseville, West St. Paul, Apple Valley, Burnsville

Web Design Arbor Bay Marketing


Alpha Omega Alpha Honor Medical Society