Table 1. Meements Used to Determine Response to Psoriasis Therapiesasur

Measurement Tool

 Definition

Psoriasis Area and Severity Index (PASI)

Measures 4 body areas (head, trunk, upper extremities, lower extremities) for the extent and severity of psoriasis.  PASI score denotes percent improvement from baseline (eg, PASI 75).

Target Lesion Assessment

Measures an identified lesion at baseline and then at designated time points throughout the trial period for:

BSA

Measurement of the percentage of BSA involved; ranges from mild (less than 2% BSA), to moderate (2%-10% BSA), to severe (greater than 10% BSA)

Physician’s Global Assessment (PGA)

A 6-category scale ranging from very severe to clear indicating physician’s overall assessment of the psoriasis severity at one time point, focusing on plaque, scaling, and erythma.

Health Assessment Questionnaire (HAQ)

A validated self-administrated questionnaire, which can also be given face-to-face in a clinical setting or in a telephone interview format by trained outcome assessors.  The Disability Index, part of the HAQ, includes 8 categories of assessment relative to the patient’s ability to perform activities.

Dermatology Life Quality Index (DLQI)

10-item dermatology-specific questionnaire; scores range from 0-30, with higher scores indicating worse quality of life.  Address: